Anticholinergic Medicines

05/07/2010

 Anticholinergic Medicines

Anticholinergic medicines block a neurochemical called acetylcholine. Anticholinergic medications help to reduce rest tremor and dystonia so they are not used for other motor symptoms of rigidity, slowness or walking problems. These medicines are not for everyone and should be used cautiously as they can cause side effects such as memory problems and confusion, especially in older patients. The following anticholinergic medications are commonly used for rest tremor.

Anticholinergic Medications:

Generic Name

Trade Name

Average Dose Range

Trihexyphenidyl

Artane

1-2 mg three times a day

Benztropine

Cogentin

1-2 mg three times a day

Biperiden

Akineton

2 mg three times a day

Ethopropazine

Parsitan

25-100 mg three times a day

 Anticholinergic side effects:

This group of medicines is not for everyone. Side effects often limit their use. Due to cognitive problems associated with this medicine they should be used with caution in older people or people on many medicines. Potential side effects include:

·         Dry mouth and eyes               

·         Memory loss               

·        Hallucinations

·         Confusion                   

·         Low blood pressure/lightheadedness

·         Nightmares                 

·         Constipation               

·         Blurred vision

·         Difficulty with urination